Moderna COVID-19 Boosters Show Preclinical Efficacy Versus South African Variant

While preclinical data show boosters to MRNA-1273 can reduce the threat of viral variants, the biotech also told investors it sees no link between its vaccine and thrombotic episodes.

Moderna vaccine
Moderna's COVID-19 variant boosters show promise in preclinical study

Moderna, Inc. revealed on 14 April that preclinical data indicate its vaccine booster candidates against the South African variant of SARS-CoV-2 increase neutralizing titers, a sign of potential efficacy against the B.1.351 variant. The company did not provide statistical data, which it said will be submitted for a peer-review publication, but saw encouraging early data for the boosters and the multivalent approach added to its MRNA-1273 vaccine.

The Cambridge, MA-based firm said during an event to update investors on its vaccine pipeline that the MRNA-1273.351 booster and...

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