Novartis Aims To Dominate Rare Renal Disorders

 
• By Elizabeth Cairns
  
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Fabhalta and atrasentan are odds-on for approval in C3 glomerulopathy and IgA nephropathy, respectively, but commercial success might be harder to come by.

Novartis

Data presented at the European Renal Association meeting today suggest that Novartis AG is heading to market with two therapies for different rare kidney diseases. Fabhalta (iptacopan) and atrasentan have shown respectable reductions in proteinuria in their respective trials, likely satisfying regulators’ requirements.

Key Takeaways

  • Novartis’s Fabhalta and atrasentan post late-breaking proteinuria data at the European Renal Association Congress

Fabhalta, an oral complement factor B inhibitor already approved for paroxysmal nocturnal hemoglobinuria, has a good chance of becoming the...

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