Genmab/AbbVie Look To Encroach On Roche’s Turf With Epkinly Follicular Lymphoma Results

 
• By Alaric DeArment
  
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The companies unveiled results showing a high overall response rate from the anti-CD20xCD3 bispecific as competition heats up between various players in the space.

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Genmab A/S and AbbVie Inc. are moving quickly to expand the market for their CD20xCD3-directed bispecific antibody, Epkinly (epcoritamab-bysp), with new topline results for the drug in follicular lymphoma (FL) just a month after the drug won accelerated approval from the US Food and Drug Administration for diffuse large B-cell lymphoma (DLBCL). The new data set Epkinly up as a potential competitor to Roche Holding AG’s anti-CD20xCD3 bispecific Lunsumio (mosunetuzumab-axgb), which received an FDA nod late last year.

Genmab and AbbVie announced 27 June topline results from the Phase I/II EPCORE NHL-1 trial testing Epkinly in 128 adults...

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