Amgen Falters In Core Immunology Business, But Help Is On The Horizon

2023 Guidance Raised Even Before Deal Closing

Sales of Amgen’s key immunology drugs Otezla and Enbrel plunged in Q1, impacted by inventory and competition, but the company will add a new blockbuster when its Horizon acquisition closes in June. 

Asphalt road ground and mountain landscape at sunset
Amgen expects to close its Horizon buy in late June • Source: Shutterstock

Amgen, Inc. reported double-digit sales declines in the first quarter for two of its big anti-inflammatory brands – Otezla (apremilast) and Enbrel (etanercept) – showing weakness in immunology, an area where the company usually thrives. However, the company will close its $27.8bn acquisition of Horizon Therapeutics plc in June, bringing in a new blockbuster product with the thyroid eye disease drug Tepezza (teprotumumab), that should help Amgen return to growth in its key therapeutic area.

Total Q1 revenues decreased 2% year-over-year to $6.11bn, just below analyst consensus of $6.12bn, primarily due to a loss in...

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