Oramed Failure Highlights Insurmountable Challenge Of Oral Insulin Delivery

Israeli Firm's Candidate Suffers Phase III Flop

Oramed's attempts to advance an oral formulation of insulin for type 2 diabetes patients have been scuppered with a Phase III fail that has sunk the stock.

Insulin wireframe of syringe and vial
Attempts to replace injections of insulin with a more convenient delivery method have failed miserably • Source: Shutterstock

Oramed Pharmaceuticals Inc. has joined the list of companies that have fallen short in the development of an oral formulation of insulin and the failure of ORMD-0801 in a late-stage diabetes trial has resulted in the Israeli firm's share price falling to the floor.

NASDAQ-listed Oramed announced topline results from a Phase III trial which compared ORMD-0801 with placebo in 710 patients with type...

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