Pfizer's Plan To Establish A $6bn Migraine Franchise

Pfizer's strategy for building a mega-blockbuster brand around Nurtec ODT involves establishing oral CGRPs as first-line treatment.

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Pfizer is looking to amp up the launch of Nurtec ODT • Source: Shutterstock

Pfizer Inc. has an ambitious commercial goal for its newly acquired migraine franchise: to develop a $6bn business out of two products, the oral CGRP inhibitor Nurtec ODT (rimegepant) for acute and preventive treatment of episodic migraine, and zavegepant, an intranasal spray for acute migraine that is pending at the US Food and Drug Administration with action expected in the first quarter. 

During an investor presentation on 12 December, the company's management team outlined plans to develop a mega-sized blockbuster business in...

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