Takeda Aims At BMS’s Sotyktu In $4bn Deal For Nimbus’s TYK2 Inhibitor

 
• By Joseph Haas
  
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Takeda’s R&D chief Andy Plump said his company has seen data indicating game-changing characteristics for TAK-279 in psoriasis. It plans to bring the candidate into Phase III next year.

$4 billion
Takeda will pay $4bn for Nimbus's Phase IIb TYK2 inhibitor • Source: Shutterstock

Takeda Pharmaceutical Co. Ltd. will go after Bristol Myers Squibb Company and its recently approved oral TYK2 inhibitor Sotyktu for moderate-to-severe psoriasis, agreeing on 13 December to pay Nimbus Therapeutics, Inc. an eye-opening $4bn up front for a Phase IIb asset from the same class, NDI034858, with plans to take it into Phase III in psoriasis next year and potentially a host of other autoimmune indications down the road.

The deal continues a string of lucrative deals for in-house discovered assets by privately held Nimbus, which focuses on computational...

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