Anthos Takes On Pharma Giants In Factor XI Anticoagulation Space

Start-Up Was First To Start A Phase III Trial

Aug 10 2022

• By Mandy Jackson

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CEO John Glasspool spoke with Scrip about why Anthos believes it has a good shot against big competitors in a market that is expected to generate blockbuster sales across multiple products.

3d illustration red blood cells circulating in the blood vessels — Anthos's first Phase III trial aims to prevent blood clots in cancer patients • Source: Shutterstock

Anthos Therapeutics Inc. is the first biopharmaceutical firm to take a Factor XI inhibitor into a Phase III clinical trial, putting the company ahead of at least two big pharma competitors hoping to bring novel anticoagulants to market with the potential to prevent blood clots without increasing bleeding risk. CEO John Glasspool told Scrip that Anthos believes its abelacimab will also be the first Factor XI product to market.

Cambridge, MA-based Anthos launched in 2019 with $250m from Blackstone Life Sciences and with a license from Novartis AG...

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