Bayer Consolidates Next-Generation Gene Editing Focus With Mammoth Deal

Pays $40m

The German major will collaborate with the US biotech to develop CRISPR gene-editing therapies, solidifying its interest in next-generation therapeutics.  

Genetic Engineering, Scientist viewing cells in a culture jar with a DNA profiles on a screen in the background illustrating gene editing
Bayer Will Gain Access To Mammoth’s Ultra-Small Cas enzymes. • Source: Alamy

Bayer AG is putting more heft behind its cell and gene therapy R&D portfolio by paying $40m upfront to Mammoth Biosciences to use its in vivo CRISPR-based gene-editing technology to develop therapies for five undisclosed indications, with an initial focus on liver-targeted diseases.

“Bringing together Mammoth’s novel CRISPR systems with our existing gene augmentation and our induced pluripotent stem cell (iPSC) platforms will...

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