Sanofi/Regeneron’s Esophagitis Data Add To Dupixent’s Winning Streak

The companies announced positive Phase III data for the drug in patients with eosinophilic esophagitis and plan to take the results to regulators in 2022.

Sanofi and Regeneron announced results from a Phase III trial of Dupixent in eosinophilic esophagitis • Source: Shutterstock

Sanofi and Regeneron Pharmaceuticals, Inc. added to the arsenal of data supporting Dupixent (dupilumab) on 25 October with Phase III results in eosinophilic esophagitis (EoE), a disease with no approved treatments but in which the drug now emerges as a leading commercial contender. The EoE data are part of a string of wins lately for Dupixent in various inflammatory diseases.

The companies announced results from their second Phase III study in EoE, which tested Dupixent at 300mg dosed once-weekly in...

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