AC Immune Keeps Faith In Alzheimer’s Breakthrough, But Spreads Risk With Parkinson’s Bet

Broadened Pipeline And Prevention Strategy

Interview: The Swiss biotech has endured many Alzheimer’s failures, but has been able to broaden its portfolio and income streams while the search for a breakthrough goes on.

Alzheimer's PET scan
AC Immune is aiming to intercept Alzheimer's years before symptoms start to appear, by which time damaged caused by beta amyloid and tau is currently irreversible.

AC Immune has suffered major disappointments in its efforts to develop an Alzheimer’s therapy in its near-20 year history, but it is hoping a switch to preventing rather that treating dementia, and a multi-pronged strategy across neurodegenerative disease, could help it finally achieve success.

Chief executive and co-founder Andrea Pfeifer has managed to keep the Switzerland-based company moving forward despite its development setbacks, and...

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Spotlight On RDCs, AOCs As Leading Novel Bioconjugates[Updated]

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EHA: Lilly’s Jaypirca Posts First Phase III Triplet Win In CLL While BTK Degraders Advance

Lilly's first Phase III triplet win opens the door to a label expansion in BTK-pretreated CLL, with analysts suggesting Jaypica could attain blockbuster status. However, the window to capitalize may be brief as next-generation BTK degraders close in with head-to-head trials.

EHA: Lilly’s Jaypirca Posts First Phase III Triplet Win In CLL While BTK Degraders Advance - Clone

Lilly's first Phase III triplet win opens the door to a label expansion in BTK-pretreated CLL, with analysts suggesting Jaypica could attain blockbuster status. However, the window to capitalize may be brief as next-generation BTK degraders close in with head-to-head trials.