Pyxis’s $152m Series B Will Push Trio Of ADCs Toward Clinic

Pyxis says its three preclinical ADCs, acquired from Pfizer and LegoChem, offer immunomodulatory effects as well as direct killing of tumor cells. It hopes all three will reach Phase I in 2022.

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Recent partner Pfizer is among the investors in Pyxis' $152m series B

Pyxis Oncology unveiled a $152m series B venture capital round on 30 March that will fund advancement of three preclinical antibody-drug conjugates (ADCs) recently acquired from LegoChem Biosciences, Inc. and Pfizer Inc. toward Phase I in 2022. The new funding also will fund its own internal immuno-oncology discovery efforts.

Pyxis launched in 2019 with a $22m series A financing backed by Bayer AG’s Leaps by Bayer program as...

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