Genentech’s New NMOSD Drug Offers At-Home Treatment, Lower Cost

List price is below competitors from Alexion, Viela Bio

Enspryng (satralizumab) is the third FDA-approved drug but only at-home treatment for neuromyelitis optica spectrum disorder; significant percentage of patients are not being treated.

FDA Approved
Enspryng previously was approved in Canada, Japan and Switzerland • Source: Shutterstock

The neuroscience group at Roche Holding AG’s Genentech, Inc.  won US Food and Drug Administration approval of its second drug in two weeks on 14 August when Enspryng (satralizumab-mwge) was cleared to treat adults with neuromyelitis optica spectrum disorder who are aquaporin-4 (AQP4) antibody positive. The interleukin-6 (IL-6) receptor inhibitor is the third NMOSD therapy approved since 2019, but it is the first treatment that can be administered in patients’ homes and at a price below its two competitors.

The list price for Enspryng, which is administered every four weeks by subcutaneous injection, is $14,615 per dose. That translates...

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