Next Generation SERDs Progress In Breast Cancer; Standing Out In The Crowd Won't Be Easy

Jun 04 2020

• By Jessica Merrill

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The class is poised to be a competitive one with Sanofi, AstraZeneca, Roche and Zentalis among the contenders developing new selective estrogen receptor degraders for HER2-negative breast cancer.

How to stand out - sales, marketing & advertising! Business concept - branding, different, original. — Several drug makers are looking to stand out in the SERD class • Source: Shutterstock

Several selective estrogen receptor degraders (SERDs) are progressing into mid-stage development as potential options for human epidermal growth factor receptor 2 (HER2)-negative, hormone receptor (HR)-positive breast cancer. Early clinical data for several of the next generation hormonal therapies were presented at the American Society of Clinical Oncology virtual meeting 29-31 May, including drugs from Sanofi, AstraZeneca PLC and Roche.

The maturing data put a renewed spotlight on the class of drugs. Another drug maker, Zentalis Pharmaceuticals, which had an...

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