After Two Jury Verdicts, Court Finds Repatha Patents Invalid

Aug 29 2019

• By Brenda Sandburg

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Delaware district court rules patent claims for antibodies targeting PCSK9 are invalid for lack of enablement; saga to continue with Amgen appeal.

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Amgen Inc. was dealt a blow in its long battle with Sanofi/Regeneron Pharmaceuticals Inc. as a district court found that its Repatha (evolocumab) patents were invalid for lack of enablement. The decision means that, for now, Sanofi and Regeneron will continue to market their competing PCSK9 inhibitor Praluent (alirocumab) in the US without worrying about potential damages.

In a 28 August opinion, Delaware District Judge Richard Andrews granted Sanofi and Regeneron's request to overturn portions of...

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