Roche's IMpower150 Gets AACR Applause But Merck's KEYNOTE-189 Big Winner

 
• By Sten Stovall
  
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Roche’s Tecentriq IMpower150 trial showed Tecentriq plus Avastin plus paclitaxel and carboplatin significantly improved progression free survival compared to Avastin and chemo alone; overall survival data will be coming later this year.

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Roche Gave IMpower150 Update In 1st Line NSCLC At AACR • Source: Shutterstock

An impressive data set on progressive free survival (PFS) demonstrated by Roche's IMpower150 study in non-squamous non-small cell lung cancer (NSCLC) was nonetheless overshadowed at the American Association for Cancer Research (AACR) meeting April 16 by rival trial presentations - and observers say the jury will remain out about IMpower150's four-drug regime until overall survival data is presented later this year.

An updated analysis from Roche’s IMpower150 showed Tecentriq (atezolizumab) and Avastin (bevacizumab) plus chemotherapies carboplatin and paclitaxel significantly improved progression-free...

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