With Entresto sales slowly climbing to $53m in third quarter, Novartis releases data supporting value of heart failure drug in preventing costly hospitalizations at the annual American Heart Association meeting.
As part of a package supporting its sluggish selling heart failure drug Entresto with payers,Novartis AG released additional data showing that the drug reduces the rate of heart failure hospitalizations and deaths related to the condition compared to the standard of care enalapril.
The FDA's approval of Entresto, which combines the neprilysin inhibitor sacubitril with the angiotensin receptor blocker valsartan, in July 2015...
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CEO Bill Anderson would not be drawn on whether the drug, currently approved for chronic kidney disease associated with type 2 diabetes, will hit a previous forecast of €3bn peak sales, but expansion into heart failure may make that figure look conservative.
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Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
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