May 15 marks the start of Dementia Awareness Week, backed by the Alzheimer's Society. Scrip has compiled a list of 10 facts industry bods interested in the space – and the wider public – might want to know about ongoing drug development for Alzheimer's disease, the leading cause of dementia.
Dementia is caused when the brain is damaged and Alzheimer's disease is the most common cause of dementia – although not all dementia is due to this condition. Other causes of dementia include vascular dementia, fronto-temporal dementia, Creutzfeldt-Jakob disease, dementia with Lewy bodies (DLB), and Korsakoff's syndrome.
The pharmaceutical industry has retained an interest in Alzheimer's R&D for more than 50 years and these top 10 facts...
GLP-1 receptor agonists could play a big role in tackling neurodegeneration and a new academic study has raised expectations of Novo Nordisk’s latest semaglutide Phase III results
Amgen’s Imdelltra for small-cell lung cancer is one of two bispecific T-cell engagers approved for solid tumors, but data at the WCLC meeting show other DLL3-targeting BiTEs may be on the way.
An academic study of GLP-1 agonist showed promise in patients with the painful skin condition but with no signs that the Danish drugmaker will pursue the indication, smaller players in the space may be interested.
As it posts third-quarter numbers that again reveal the decline of revenues from its multiple sclerosis portfolio, the US biotech major is entering into the hot area of targeted protein degradation to boost its immunology and neurology pipeline.
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Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
![Spotlight On RDCs, AOCs As Leading Novel Bioconjugates[Updated]](https://web.insights.norstella-labs.com/resizer/v2/3M7ZAWZOBNK7NG4A4WDOIFG6DU.jpg?smart=true&auth=392a1fdb3cfacb29445720c412410e598dbcc5f90f14857652cd498bd0faa0fb&width=400&height=225)
