As COVID-19 Successes Fuel R&D, Efforts Focus On mRNA Optimization

In the third part of this special focus on mRNA manufacturing, In Vivo looks at the many directions mRNA platforms can expand, with a major focus on optimizing cellular microenvironments for safety and efficacy.      

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Researchers in industry and academia on a wide array of applications for mRNA lipid nanoparticles is likely to accelerate thanks to the mRNA COVID-19 vaccines that Pfizer Inc./BioNTech SE and Moderna, Inc. developed in 2020.

After recapping the development of Pfizer/BioNTech’s Comirnaty COVID-19 vaccine, Oliver Hennig, BioNTech senior VP operations, told the International Society for...

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